In the new program, twelve well-known Dutch people embark on an adventure in a breathtaking location on the Mediterranean Sea. They compete in a game full of dilemmas, temptation, and revenge, surrounded by temples, ruins, and nature. The game revolves around a single mysterious object: Pandora's Box. And the participants are better off leaving it closed, because, just like in the myth, opening it has ominous consequences.

The game revolves not only around Pandora, but also features other Greek mythical figures. The challenges during the episodes are inspired by Sisyphus, and exciting encounters with Medusa's gaze take place. Each episode culminates in a confrontation with two cursed players fighting for survival, while competing against each other in a duel to avoid elimination. This means new relationships, alliances, and above all, unpredictability every week.